Publications

 

Check out our recent work below.

2024

  • Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology

    Filandr F, Sarpe V, Raval S, Crowder DA, Khan MF, Douglas P, Khan MF, Coales S, Viner R, Syed A, Tainer JA, Lees-Miller SP, Schriemer DC.

    Nat Commun. 2024 Mar 11;15(1):2200

  • The HisRS-like domain of GCN2 is a pseudoenzyme that can bind uncharged tRNA

    Yin JZ, Keszei AFA, Houliston S, Filandr F, Beenstock J, Daou S, Kitaygorodsky J, Schriemer DC, Mazhab-Jafari MT, Gingras AC, Sicheri F.

    Structure. 2024 Mar 22:S0969-2126(24)00081-9

2023

  • High-Efficiency Enrichment by Saturating Nanoliters of Protein Affinity Media

    Raval S, Douglas P, Laurent D, Khan MF, Lees-Miller SP, Schriemer DC.

    Anal Chem. 2023 Oct 31;95(43):15884-15892.

  • Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity

    Syed A, Filandr F, Patterson-Fortin J, Bacolla A, Ravindranathan R, Zhou J, McDonald DT, Albuhluli ME, Verway-Cohen A, Newman JA, Tsai MS, Jones DE, Schriemer DC, D'Andrea AD, Tainer JA.

    Nucleic Acids Res. 2023 Oct 13;51(18):9920-9937.

  • All-in-One Pseudo-MS3 Method for the Analysis of Gas-Phase Cleavable Protein Crosslinking Reactions

    Brodie NI, Sarpe V, Crowder DA, Schriemer D.

    J Am Soc Mass Spectrom. 2023 Oct 4;34(10):2146-2155.

  • Mouse Model of Fragile X Syndrome Analyzed by Quantitative Proteomics: A Comparison of Methods.

    Filandrova R, Douglas P, Zhan X, Verhey TB, Morrissy S, Turner RW, Schriemer DC.

    J Proteome Res. 2023 Sep 1;22(9):3054-3067.

  • High-Sensitivity Proteome-Scale Searches for Crosslinked Peptides Using CRIMP 2.0

    Crowder DA, Sarpe V, Amaral BC, Brodie NI, Michael ARM, Schriemer DC.

    High-Sensitivity Proteome-Scale Searches for Crosslinked Peptides Using CRIMP 2.0.

    Anal Chem. 2023 Apr 18;95(15):6425-6432.

  • Apparatus for Automated Continuous Hydrogen Deuterium Exchange Mass Spectrometry Measurements from Milliseconds to Hours

    Anacleto J, Lento C, Sarpe V, Maqsood A, Mehrazma B, Schriemer D, Wilson DJ.

    Anal Chem. 2023 Mar 7;95(9):4421-4428.

2022

2021

  • Improving Spectral Validation Rates in Hydrogen-Deuterium Exchange Data Analysis

    Raval S, Sarpe V, Hepburn M, Crowder DA, Zhang T, Viner R, Schriemer DC.

    Anal Chem. 2021 Mar 9;93(9):4246-4254.

  • IMProv: A Resource for Cross-link-Driven Structure Modeling that Accommodates Protein Dynamics

    Ziemianowicz DS, Saltzberg D, Pells T, Crowder DA, Schräder C, Hepburn M, Sali A, Schriemer DC.

    Mol Cell Proteomics. 2021;20:100139.

  • The active DNA-PK holoenzyme occupies a tensed state in a staggered synaptic complex

    Hepburn M, Saltzberg DJ, Lee L, Fang S, Atkinson C, Strynadka NCJ, Sali A, Lees-Miller SP, Schriemer DC.

    Structure. 2021 May 6;29(5):467-478.e6.